Nucleation and spreading of a heterochromatic domain in fission yeast

Chromosomes contain large heterochromatin domains. Here, the authors measure the kinetics of heterochromatin formation in fission yeast and show both global and local feedbacks by nucleosome-bound enzymes are important for formation and stability of the large heterochromatin domains.

Bibliographic Details
Main Authors: Michaela J. Obersriebnig, Emil M. H. Pallesen, Kim Sneppen, Ala Trusina, Geneviève Thon
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11518