Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity.

Recent advances in the field of non-invasive optical imaging have included the development of contrast agents that report on the activity of enzymatic targets associated with disease pathology. In particular, proteases have proven to be ideal targets for development of optical sensors for cancer. Re...

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Bibliographic Details
Main Authors: Galia Blum, Robby M Weimer, Laura E Edgington, Walter Adams, Matthew Bogyo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2712068?pdf=render