Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes

Abstract Background A-to-I RNA editing diversifies the transcriptome and has multiple downstream functional effects. Genetic variation contributes to RNA editing variability between individuals and has the potential to impact phenotypic variability. Results We analyze matched genetic and transcripto...

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Bibliographic Details
Main Authors: Eddie Park, Yan Jiang, Lili Hao, Jingyi Hui, Yi Xing
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02287-1