A transcriptomic atlas of aged human microglia

Aging is associated with various changes in the brain, including transcription alteration. Here, Bradshaw and colleagues describe the transcriptome of aged human cortical microglia, and show age-related gene expression as related to neurodegeneration.

Bibliographic Details
Main Authors: Marta Olah, Ellis Patrick, Alexandra-Chloe Villani, Jishu Xu, Charles C. White, Katie J. Ryan, Paul Piehowski, Alifiya Kapasi, Parham Nejad, Maria Cimpean, Sarah Connor, Christina J. Yung, Michael Frangieh, Allison McHenry, Wassim Elyaman, Vlad Petyuk, Julie A. Schneider, David A. Bennett, Philip L. De Jager, Elizabeth M. Bradshaw
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02926-5