Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet

The peroxisome proliferator-activated receptor-γ coactivators (PGC-1) are transcriptional coactivators with an important role in mitochondrial biogenesis and regulation of genes involved in the electron transport chain and oxidative phosphorylation in oxidative tissues including cardiac tissue. Thes...

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Bibliographic Details
Main Authors: Gregor McCombie, Gema Medina-Gomez, Christopher J Lelliott, Antonio Vidal-Puig, Julian L Griffin
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/2/2/366