Correlation between CTLA-4 and CD40 gene polymorphisms and their interaction in graves’ disease in a Chinese Han population

Correlation between CTLA-4 and CD40 gene polymorphisms and their interaction in graves’ disease in a Chinese Han population

Abstract Background Single-nucleotide polymorphism (SNP) haplotype and SNP-SNP interactions of CTLA-4 and CD40 genes, with susceptibility to Graves’ disease (GD), were explored in a Chinese Han population. Methods SNP were genotyped by high resolution melting (HRM). Use the method of Pearson χ2 test...

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Bibliographic Details
Main Authors: Xiaoming Chen, Zhuoqing Hu, Meilian Liu, Huaqian Li, Chanbo Liang, Wei Li, Liwen Bao, Manyang Chen, Ge Wu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Medical Genetics
Subjects:
Graves’ disease
CD40
CTLA-4
Genetic polymorphism
Online Access:http://link.springer.com/article/10.1186/s12881-018-0665-y

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http://link.springer.com/article/10.1186/s12881-018-0665-y

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