Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

Introduction: Each year, a disproportionate number of the total seasonal influenza-related hospitalizations (90%) and deaths (70%) occur among adults who are >65 years old. Inflammasome activation has been shown to be important for protection against influenza infection in animal models but h...

Full description

Bibliographic Details
Main Authors: Stephen N. Crooke, Krista M. Goergen, Inna G. Ovsyannikova, Richard B. Kennedy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2021.719103/full