A new method for measuring cholesterol efflux capacity uses stable isotope-labeled, not radioactive-labeled, cholesterol

A new method for measuring cholesterol efflux capacity uses stable isotope-labeled, not radioactive-labeled, cholesterol

The incidence of cardiovascular events correlates inversely with cholesterol efflux capacity (CEC) more than with HDL-cholesterol level. The measurement of CEC is used to qualify cardiovascular disease risk and is conventionally performed with radioisotope (RI)-labeled cholesterol. Here, we establis...

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Bibliographic Details
Main Authors: Tomo Shimizu, Osamu Miyazaki, Takeo Iwamoto, Tomoyuki Usui, Ryo Sato, Chika Hiraishi, Hiroshi Yoshida
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein
reverse cholesterol transport
high density lipoprotein
mass spectrometry
stable isotope tracers
[d7]cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032294X

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http://www.sciencedirect.com/science/article/pii/S002222752032294X

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