Evaluation of sodium nitroprusside for controlled hypotension in children during surgery

Purpose. (1) To define the onset and offset of the blood-pressure-lowering effects of sodium nitroprusside (SNP) for use in developing instructions for dose titration in children undergoing a surgical or medical procedure, and (2) to assess the safety of SNP administration in pediatric patients requ...

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Bibliographic Details
Main Authors: David R Drover, Gregory B Hammer, Jeffrey Scott Barrett, Carol A Cohane, Tammy eReece, Anne eZajicek, Scott eSchulman
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00136/full