Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage (GATE-ICH): Study Protocol for a Multicenter Randomized, Controlled, Assessor-Blinded Trial

Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage (GATE-ICH): Study Protocol for a Multicenter Randomized, Controlled, Assessor-Blinded Trial

Introduction: Brain edema after acute intracerebral hemorrhage (ICH) plays a critical role in the secondary injury of ICH and may heighten the potential for a poor outcome. This trial aims to explore the efficacy of small doses of oral glibenclamide in perihematomal edema (PHE) and the prognosis of...

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Bibliographic Details
Main Authors: Jingjing Zhao, Fang Yang, Changgeng Song, Li Li, Xiai Yang, Xiaofeng Wang, Liping Yu, Jun Guo, Kangjun Wang, Feng Fu, Wen Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neurology
Subjects:
perihematomal edema
intracerebral hemorrhage
glibenclamide
prognosis
clinical trial
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.656520/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.656520/full

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