Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro

Background and Objective: YB-1 is a transcription and oncogenic factor capable of binding to DNA and RNA performing versatile functions within normal and cancer cells. Some studies reported the binding of YB-1 with a collagenases gene promoter and influencing their expression. In addition, the role...

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Bibliographic Details
Main Authors: Wisam Nabeel Ibrahim, Abd Almonem Doolaanea, Mohammad Syaiful Bahari Bin Abdull Rasad
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/7/1/7