Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial–Mesenchymal Transition of Epithelial Cells

Increasing evidence and indications showed that cell fusion is crucial in tumor development and metastasis, and hypoxia, a closely linked factor to tumor microenvironment, which can lead to EMT, induces angiogenesis and metastasis in tumor growth. However, the relationship between hypoxia and fusion...

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Bibliographic Details
Main Authors: Chun-ming Huang, Ting-lin Yan, Zhi Xu, Meng Wang, Xiao-cheng Zhou, Er-hui Jiang, Ke Liu, Zhe Shao, Zheng-Jun Shang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/5015203