Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

Signaling between neurons in the human central nervous system (CNS) is accomplished through a highly interconnected network of presynaptic and postsynaptic elements essential in the conveyance of electrical and neurochemical information. One recently characterized core postsynaptic element essential...

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Bibliographic Details
Main Authors: Peter N. Alexandrov, Yuhai Zhao, Vivian Jaber, Lin Cong, Walter J. Lukiw
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Neurology
Subjects:
5x familial Alzheimer’s disease transgenic mice
42 amino acid amyloid-beta peptides
aluminum sulfate
Alzheimer’s disease
autism spectrum disorder
bipolar disorder-schizophrenia
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00670/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00670/full

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