In Vivo and In Vitro Elution of Analgesics from Multilayered Poly(D,L)-lactide-co-glycolide Nanofibers Incorporated Ureteral Stents

We develop novel analgesic-eluting nanofiber-incorporated ureteral stents that offer sustained release of lidocaine and ketorolac for local drug delivery. Lidocaine and poly(D,L)-lactide-co-glycolide (PLGA) were dissolved in hexafluoroisopropanol and were electrospun into nonwoven nanofibers onto th...

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Bibliographic Details
Main Authors: Yi-Chia Lin, Kuo-Sheng Liu, Demei Lee, Min-Jhan Li, Shih-Jung Liu, Hiroshi Ito
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2018/4943210