Role of Polycomb Proteins in Regulating HSV-1 Latency

Herpes simplex virus (HSV) establishes a latent infection within sensory neurons of humans. Latency is characterized by the transcriptional repression of lytic genes by the condensation of lytic gene regions into heterochromatin. Recent data suggest that facultative heterochromatin predominates, and...

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Bibliographic Details
Main Authors: David Bloom, Dane Phelan, Harald Messer, Zachary Watson, Adit Dhummakupt
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Viruses
Subjects:
HSV
PRC
Online Access:http://www.mdpi.com/1999-4915/5/7/1740