Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat.

Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat.

Adeno associated virus (AAV) is well known for its ability to deliver transgenes to retina and to mediate improvements in animal models and patients with inherited retinal disease. Although the field is less advanced, there is growing interest in AAV's ability to target cells of the anterior se...

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Bibliographic Details
Main Authors: Barbara Bogner, Sanford L Boye, Seok Hong Min, James J Peterson, Qing Ruan, Zhonghong Zhang, Herbert A Reitsamer, William W Hauswirth, Shannon E Boye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4460001?pdf=render

Internet

http://europepmc.org/articles/PMC4460001?pdf=render

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