Nanoscopic subcellular imaging enabled by ion beam tomography

Nanoscopic subcellular imaging enabled by ion beam tomography

Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in 3D and sub-25 nm accuracy, called Ion Beam Tomogra...

Full description

Bibliographic Details
Main Authors: Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20753-5

Internet

https://doi.org/10.1038/s41467-020-20753-5

Similar Items