Study of major genetic factors involved in pituitary tumorigenesis and their impact on clinical and biological characteristics of sporadic somatotropinomas and non-functioning pituitary adenomas

Study of major genetic factors involved in pituitary tumorigenesis and their impact on clinical and biological characteristics of sporadic somatotropinomas and non-functioning pituitary adenomas

Genetic and functional aberrations of guanine nucleotide-binding protein, alpha stimulating (GNAS), aryl hydrocarbon receptor interacting protein (AIP), and pituitary tumor transforming gene (PTTG) are among the most prominent events in pituitary tumorigenesis. A cohort of Brazilian patients with so...

Full description

Bibliographic Details
Main Authors: R.K. Foltran, P.V.G.H. Amorim, F.H. Duarte, I.P.P. Grande, A.C.T.B. Freire, F.P. Frassetto, J.B. Dettoni, V.A. Alves, I. Castro, E.B. Trarbach, M.D. Bronstein, R.S. Jallad
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Somatotropinomas
Non-functioning pituitary adenomas
PTTG
AIP
GNAS1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900601&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900601&lng=en&tlng=en

Similar Items