The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase

Abstract The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved in carcinogenesis. However, its functional role in other cellular processes is poorly understood. To address this question, we perfor...

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Bibliographic Details
Main Authors: Alexandra Daks, Alexey Petukhov, Olga Fedorova, Oleg Shuvalov, Alena Kizenko, Elizaveta Tananykina, Elena Vasileva, Oleg Semenov, Andrew Bottrill, Nickolai Barlev
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03871-w

Internet

https://doi.org/10.1038/s41419-021-03871-w

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