Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein.

Soluble extracellular proteins usually do not enter the endogenous human leukocyte antigen (HLA) I-dependent presentation pathway of antigen-presenting cells, strictly impeding their applicability for the re-stimulation of protein-specific CD8(+) cytotoxic T lymphocytes (CTL). Here we present for th...

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Bibliographic Details
Main Authors: Sascha Barabas, Regina Gary, Tanja Bauer, Juha Lindner, Petra Lindner, Birgit Weinberger, Wolfgang Jilg, Hans Wolf, Ludwig Deml
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2572144?pdf=render