CD4+CD25+CD127 regulatory cells play multiple roles in maintaining HIV-1 p24 production in patients on long-term treatment: HIV-1 p24-producing cells and suppression of anti-HIV immunity

Background: A major question when attempting to eradicate and treat HIV-1 infection is how to reactivate latent proviruses. Stimulating HIV-1-specific cytolytic T lymphocytes (CTL) has been shown to facilitate the elimination of the latent viral reservoir after viral reactivation. Regulatory T (Treg...

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Bibliographic Details
Main Authors: Yan-Mei Jiao, Cui-e Liu, Li-Jing Luo, Wei-Jun Zhu, Tong Zhang, Li-Guo Zhang, Li-Shan Su, Hong-Jun Li, Hao Wu
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:International Journal of Infectious Diseases
Subjects:
ART
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971215001423