Derivation of iPSCs after culture of human dental pulp cells under defined conditions.

Human dental pulp cells (hDPCs) are a promising resource for regenerative medicine and tissue engineering and can be used for derivation of induced pluripotent stem cells (iPSCs). However, current protocols use reagents of animal origin (mainly fetal bovine serum, FBS) that carry the potential risk...

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Main Authors: Tomoko Takeda-Kawaguchi, Ken Sugiyama, Shunji Chikusa, Kazuki Iida, Hitomi Aoki, Naritaka Tamaoki, Daijiro Hatakeyama, Takahiro Kunisada, Toshiyuki Shibata, Noemi Fusaki, Ken-Ichi Tezuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115392