Temporal and regional regulation of gene expression by calcium-stimulated adenylyl cyclase activity during fear memory.

Temporal and regional regulation of gene expression by calcium-stimulated adenylyl cyclase activity during fear memory.

The Ca2+-stimulated adenylyl cyclases (ACs), AC1 and AC8, are key components of long-term memory processing. AC1 and AC8 double knockout mice (Adcy1(-/-)Adcy8(-/-); DKO) display impaired fear memory processing; the mechanism of this impairment is largely unknown.We hypothesize that the Ca2+-stimulat...

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Bibliographic Details
Main Authors: Lindsay Wieczorek, James W Maas, Lisa M Muglia, Sherri K Vogt, Louis J Muglia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954788?pdf=render

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http://europepmc.org/articles/PMC2954788?pdf=render

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