CAR modulates E-cadherin dynamics in the presence of adenovirus type 5.

Adenovirus (Ad) serotype 5 (Ad5) fiber competitively binds to the coxsackievirus and Ad receptor (CAR) to attach Ad5 to target cells and also disrupts cell junctions and facilitates virus escape at a late stage in Ad5 infection. Here we demonstrate that paracellular permeability in MCF7 and CAR over...

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Bibliographic Details
Main Authors: Fawziyah Hussain, Penny E Morton, Marjolein Snippe, Janis Sullivan, Charlotte Farmer, Marisa L Martin-Fernandez, Maddy Parsons, George Santis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3151283?pdf=render