Telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking history.

Chromoendoscopy with Lugol iodine staining provides important information on the development of squamous cell carcinoma (SCC). In particular, distinct iodine-unstained lesions (DIULs) larger than 10 mm show a high prevalence in high-grade intraepithelial neoplasia. It has also been reported that ina...

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Main Authors: Junko Aida, Akira Yokoyama, Naotaka Shimomura, Ken-ichi Nakamura, Naoshi Ishikawa, Masanori Terai, Steven Poon, Masaaki Matsuura, Mutsunori Fujiwara, Motoji Sawabe, Tomio Arai, Kaiyo Takubo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646776?pdf=render