Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder

Platelet hyperserotonemia in a subset of Autism Spectrum Disorder (ASD) probands, efficacy of selective serotonin reuptake inhibitors (SSRIs) in reducing behavioral deficits and gender-bias in normal serotonin (5-hydroxy tryptamine or 5-HT) synthesis suggest disruption in stringent regulation of ser...

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Main Authors: Barnali Chakraborti, Deepak Verma, Subhrangshu Guhathakurta, Preeti Jaiswal, Asem Surindro Singh, Swagata Sinha, Saurabh Ghosh, Kanchan Mukhopadhyay, Kochupurackal P. Mohanakumar, Usha Rajamma
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01375/full