Rare or Overlooked? Structural Disruption of Regulatory Domains in Human Neurocristopathies

In the last few years, the role of non-coding regulatory elements and their involvement in human disease have received great attention. Among the non-coding regulatory sequences, enhancers are particularly important for the proper establishment of cell type–specific gene-expression programs. Further...

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Bibliographic Details
Main Authors: Víctor Sánchez-Gaya, Maria Mariner-Faulí, Alvaro Rada-Iglesias
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00688/full