Downregulation of vimentin intermediate filaments affect human mesenchymal stem cell adhesion and formation of cellular projections

Downregulation of vimentin intermediate filaments affect human mesenchymal stem cell adhesion and formation of cellular projections

Mesenchymal stem cells hold great promise as a therapeutic cell source for a variety of diseases such as osteoarthritis and degenerative disc disease. Their unique homing ability and multipotentiality play key roles in their applications in medicine. Specifically, hMSCs capability to adhere and migr...

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Bibliographic Details
Main Authors: Poonam Sharma, Shalise Burch, Tejasvi Peesay, Susan M. Hamilla, Adam H. Hsieh, Carlos Luna Lopez
Format: Article
Language:English
Published: AIMS Press 2020-11-01
Series:AIMS Bioengineering
Subjects:
mesenchymal stem cells
vimenti
actin
cytoskeleton
cell adhesion
intermediate filaments
Online Access:http://www.aimspress.com/article/10.3934/bioeng.2020023/fulltext.html

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http://www.aimspress.com/article/10.3934/bioeng.2020023/fulltext.html

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