Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model

Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model

Antrodan, a unique protein-bound polysaccharide derived from the fungal mycelia of Antrodia cinnamomea, has been reported to exhibit antitumor and anti-metastatic effects on Lewis lung carcinoma (LLC) cells through direct action and immunomodulation in vitro. In this study, we investigated the combi...

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Bibliographic Details
Main Authors: Pei-Chun Chen, Chin-Chu Chen, Yaw-Bee Ker, Chi-Huang Chang, Charng-Cherng Chyau, Miao-Lin Hu
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
Antrodia cinnamomea
antrodan
Lewis lung carcinoma
metastasis
MMPs
STAT3
MAPK
ERK
JNK
p38
immunity
Online Access:http://www.mdpi.com/1422-0067/19/6/1565

Internet

http://www.mdpi.com/1422-0067/19/6/1565

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