In vitro Antibacterial Activity of an FDA-Approved H+-ATPase Inhibitor, Bedaquiline, Against Streptococcus mutans in Acidic Milieus

In vitro Antibacterial Activity of an FDA-Approved H+-ATPase Inhibitor, Bedaquiline, Against Streptococcus mutans in Acidic Milieus

BackgroundDental caries is an acid-related disease. Current anti-caries agents mainly focus on the bacteriostatic effect in a neutral environment and do not target acid-resistant microorganisms related to caries in acidic milieus.ObjectivesTo assess the in vitro antibacterial activities of bedaquili...

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Bibliographic Details
Main Authors: Meng Zhang, Wenqian Yu, Shujing Zhou, Bing Zhang, Edward Chin Man Lo, Xin Xu, Dongjiao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
caries
antibacteria activity
Streptococcus mutans
acid resistance bacteria
acidic environment
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.647611/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.647611/full

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