Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans

Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans

Abstract Background Dyslipidaemia is a major risk factor for atherosclerosis and cardiovascular diseases. The molecular mechanisms that translate dyslipidaemia into atherogenesis and reliable markers of its progression are yet to be fully elucidated. To address this issue, we conducted a comprehensi...

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Bibliographic Details
Main Authors: Mariola Olkowicz, Izabela Czyzynska-Cichon, Natalia Szupryczynska, Renata B. Kostogrys, Zdzislaw Kochan, Janusz Debski, Michal Dadlez, Stefan Chlopicki, Ryszard T. Smolenski
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Subjects:
Dyslipidaemia
Atherosclerosis
Metabolome
Proteome
Pathological mechanisms
Serological biomarkers
Online Access:https://doi.org/10.1186/s12967-020-02663-8

Internet

https://doi.org/10.1186/s12967-020-02663-8

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