NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis

NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis

Abstract NF-κB is a well-characterized transcription factor, widely known for its roles in inflammation and immune responses, as well as in control of cell division and apoptosis. However, its function in β-cells is still being debated, as it appears to depend on the timing and kinetics of its activ...

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Bibliographic Details
Main Authors: Dror Sever, Anat Hershko-Moshe, Rohit Srivastava, Roy Eldor, Daniel Hibsher, Hadas Keren-Shaul, Ido Amit, Federico Bertuzzi, Lars Krogvold, Knut Dahl-Jørgensen, Iddo Z. Ben-Dov, Limor Landsman, Danielle Melloul
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-020-00386-9

Internet

https://doi.org/10.1038/s41420-020-00386-9

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