Time-dependent effect of 1,6-hexanediol on biomolecular condensates and 3D chromatin organization
Abstract Background Biomolecular condensates have been implicated in multiple cellular processes. However, the global role played by condensates in 3D chromatin organization remains unclear. At present, 1,6-hexanediol (1,6-HD) is the only available tool to globally disrupt condensates, yet the condi...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-08-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-021-02455-3 |