Profiling the Targets of Protective CD8+ T Cell Responses to Infection

Profiling the Targets of Protective CD8+ T Cell Responses to Infection

T cells are critical effectors of host immunity that target intracellular pathogens, such as the causative agents of HIV, tuberculosis, and malaria. The development of vaccines that induce effective cell-mediated immunity against such pathogens has proved challenging; for tuberculosis and malaria, m...

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Bibliographic Details
Main Authors: Joseph T. Bruder, Ping Chen, Greg Ekberg, Emily C. Smith, Christopher A. Lazarski, Bennett A. Myers, Jessica Bolton, Martha Sedegah, Eileen Villasante, Thomas L. Richie, C. Richter King, Joao C. Aguiar, Denise L. Doolan, Douglas E. Brough
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
vaccine
T cell
malaria
adenovirus
antigen
screen
vector
antigen discovery
viral vector
Online Access:http://www.sciencedirect.com/science/article/pii/S232905011730092X

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http://www.sciencedirect.com/science/article/pii/S232905011730092X

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