Silica-coated magnetic nanoparticles activate microglia and induce neurotoxic d-serine secretion

Abstract Background Nanoparticles have been studied for brain imaging, diagnosis, and drug delivery owing to their versatile properties due to their small sizes. However, there are growing concerns that nanoparticles may exert toxic effects in the brain. In this study, we assessed direct nanotoxicit...

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Bibliographic Details
Main Authors: Tae Hwan Shin, Da Yeon Lee, Balachandran Manavalan, Shaherin Basith, Yun-Cheol Na, Cheolho Yoon, Hyeon-Seong Lee, Man Jeong Paik, Gwang Lee
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12989-021-00420-3