An experimental and computational study of the effect of ActA polarity on the speed of Listeria monocytogenes actin-based motility.

Listeria monocytogenes is a pathogenic bacterium that moves within infected cells and spreads directly between cells by harnessing the cell's dendritic actin machinery. This motility is dependent on expression of a single bacterial surface protein, ActA, a constitutively active Arp2,3 activator...

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Bibliographic Details
Main Authors: Susanne M Rafelski, Jonathan B Alberts, Garrett M Odell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2699634?pdf=render