An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles

OBJECTIVES: Pituitary-dependent hyperadrenocorticism is the most common cause of naturally occurring hypercortisolism in dogs. CRHR1 expression in human and dog corticotrophinomas suggested that this gene affects pituitary tumorigenesis. The present study aimed to investigate mutations in the CRHR1...

Full description

Bibliographic Details
Main Authors: Viviani De-Marco, Luciani R. Carvalho, Mariana F. Guzzo, Paulo S.L. Oliveira, Larissa G. Gomes, Berenice B. Mendonca
Format: Article
Language:English
Published: Faculdade de Medicina / USP
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017000900575&lng=en&tlng=en