Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entry

<p>Abstract</p> <p>Background</p> <p>The spike protein (S) of SARS Coronavirus (SARS-CoV) mediates entry of the virus into target cells, including receptor binding and membrane fusion. Close to or in the viral membrane, the S protein contains three distinct motifs: a ju...

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Bibliographic Details
Main Authors: van Kasteren Puck, Broer Rene, Corver Jeroen, Spaan Willy
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/230