Macrocycle Therapeutics to Treat Life-threatening Diseases
Polyphor's macrocycle platform led to the discovery of novel antibiotics addressing specifically Gramnegative bacteria by targeting outer membrane proteins. Furthermore, POL6014, an inhibitor of neutrophile elastase and balixafortide, a CXCR4 inhibitor have been discovered and developed from th...
Main Authors: | , , , |
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Format: | Article |
Language: | deu |
Published: |
Swiss Chemical Society
2021-06-01
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Series: | CHIMIA |
Subjects: | |
Online Access: | https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00009 |