The protective effect against extracellular histones afforded by long-pentraxin PTX3 as a regulator of NETs
Pentraxin 3 (PTX3) is a soluble pattern recognition molecule which plays critical roles in innate immunity. Its fundamental functions include recognition of microbes, activation of complement cascades and opsonization. The findings that PTX3 is one of the component proteins in neutrophil extracellul...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-09-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00344/full |