Digital Pathology Scoring of Immunohistochemical Staining Reliably Identifies Prognostic Markers and Anatomical Associations in a Large Cohort of Oral Cancers

Digital Pathology Scoring of Immunohistochemical Staining Reliably Identifies Prognostic Markers and Anatomical Associations in a Large Cohort of Oral Cancers

Utilizing digital pathology algorithms for the objective quantification of immunohistochemical staining, this study aimed to identify robust prognostic biomarkers for oral cancer. Tissue microarrays with specimens of a large cohort of oral squamous cell carcinoma (n=222) were immunohistochemically s...

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Bibliographic Details
Main Authors: Julius Moratin, Andreas Mock, Sonja Obradovic, Karl Metzger, Christa Flechtenmacher, Karim Zaoui, Stefan Fröhling, Dirk Jäger, Jürgen Krauss, Jürgen Hoffmann, Kolja Freier, Dominik Horn, Jochen Hess, Christian Freudlsperger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
immune cells
automated
quantification
biomarker
head and neck squamous cell carcinoma
oral squamous cell carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.712944/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.712944/full

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