IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis

Abstract Myeloid cells, key players in atherosclerosis, take up and present antigens, leading to systemic and local T cell activation. The recruitment and activation of immune cells to the aorta in atherosclerosis is regulated by adhesion molecules, chemokines and cytokines. IL-27R is an immunoregul...

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Bibliographic Details
Main Authors: Iuliia O. Peshkova, Aliia R. Fatkhullina, Zbigniew Mikulski, Klaus Ley, Ekaterina K. Koltsova
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01828-8