The Role of Complement in Myocardial Infarction Reperfusion Injury: An Underappreciated Therapeutic Target

This article reviews the pathogenetic role of the complement system in myocardial infarction reperfusion injury. The complement activation pathways involved in myocardial tissue injury are identified, as are the complement-derived effector molecules. The results of past anti-complement therapies are...

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Bibliographic Details
Main Author: Carl-Wilhelm Vogel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.606407/full