Nobiletin, a Polymethoxy Flavonoid, Protects Against Cardiac Hypertrophy Induced by Pressure-Overload via Inhibition of NAPDH Oxidases and Endoplasmic Reticulum Stress

Nobiletin, a Polymethoxy Flavonoid, Protects Against Cardiac Hypertrophy Induced by Pressure-Overload via Inhibition of NAPDH Oxidases and Endoplasmic Reticulum Stress

Background/Aims: An increase in oxidative stress has been implicated in the pathophysiology of pressure-overload induced cardiac hypertrophy. Nobiletin (NOB), extracted from the fruit peel of citrus, possesses anti-oxidative property. Our study aimed to investigate the protective role of NOB in the...

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Bibliographic Details
Main Authors: Ning Zhang, Wen-Ying Wei, Zheng Yang, Yan Che, Ya-Ge Jin, Hai-Han Liao, Sha-sha Wang, Wei Deng, Qi-Zhu Tang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Nobiletin
Cardiac hypertrophy
NAPDH oxidase
Endoplasmic reticulum stress
Online Access:http://www.karger.com/Article/FullText/478960

Internet

http://www.karger.com/Article/FullText/478960

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