Effects of metformin on CD133+ colorectal cancer cells in diabetic patients.

In diabetic patients complicated with colorectal cancer (CRC), metformin treatment was reported to have diverse correlation with CRC-specific mortality. In laboratory studies, metformin was reported to affect the survival of cancer stem cells (CSCs) in breast and pancreatic cancers and glioblastoma....

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Bibliographic Details
Main Authors: Yanfei Zhang, Meiping Guan, Zongji Zheng, Qian Zhang, Fang Gao, Yaoming Xue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836781?pdf=render