Current and emerging strategies for the management of imatinib-refractory advanced gastrointestinal stromal tumors
Since its approval by the US Food and Drug Administration in February 2002, the tyrosine kinase inhibitor, imatinib, has become the standard of care for patients with metastatic or unresectable KIT-positive gastrointestinal stromal tumors (GISTs). Imatinib functions by blocking the adenosine triphos...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-09-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758834012450935 |