An Interaction with Ewing’s Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer

Summary: More than 50% of prostate tumors have a chromosomal rearrangement resulting in aberrant expression of an oncogenic ETS family transcription factor. However, mechanisms that differentiate the function of oncogenic ETS factors expressed in prostate tumors from non-oncogenic ETS factors expres...

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Bibliographic Details
Main Authors: Vivekananda Kedage, Nagarathinam Selvaraj, Taylor R. Nicholas, Justin A. Budka, Joshua P. Plotnik, Travis J. Jerde, Peter C. Hollenhorst
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716313705