Dihydropyrimidine dehydrogenase gene variation and its association with 5-fluorouracil toxicity in colorectal patients
Purpose: Dihydropyrimidine dehydrogenase (DPD), an enzyme translated by DPD gene (DPYD), has a critical role in the metabolism of 5-fluorouracil (5FU). In this study we aimed to investigate the frequency of the IVS14+1 G>A, 2194G>A, 2846 A>T mutations in the DPYD gene in colorectal cancer p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2018-09-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Online Access: | http://www.waocp.org/journal/index.php/apjcb/article/view/142 |