Sources of variation in ancestral sequence reconstruction for HIV-1 envelope genes

Sources of variation in ancestral sequence reconstruction for HIV-1 envelope genes

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We characterized the variation in the reconstructed ancestor of 118 HIV-1 envelope gene sequences arising from the methods used for (a) estimating and (b) rooting the phylogenetic tree, and (c) reconstructing the ancestor on that tree, from (d) the sequence format, and from (e) the number of input s...

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Bibliographic Details
Main Authors: James I. Mullins, Allen G. Rodrigo, Mark A. Jensen, Laura Heath, Yi Liu, David C. Nickle, Howard A. Ross
Format: Article
Language:English
Published: SAGE Publishing 2006-01-01
Series:Evolutionary Bioinformatics
Subjects:
ancestral sequence reconstruction
center of tree
taxon sampling
rational vaccine design
HIV-1
Online Access:http://la-press.com/article.php?article_id=152

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http://la-press.com/article.php?article_id=152

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