FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha.

FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha.

BACKGROUND: Fibroblast growth factor 2 (FGF2) is a major angiogenic factor involved in angiogenesis and arteriogenesis, however the regulation of its expression during these processes is poorly documented. FGF2 mRNA contains an internal ribosome entry site (IRES), a translational regulator expected...

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Bibliographic Details
Main Authors: Caroline Conte, Elodie Riant, Céline Toutain, Françoise Pujol, Jean-François Arnal, Françoise Lenfant, Anne-Catherine Prats
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2518102?pdf=render

Internet

http://europepmc.org/articles/PMC2518102?pdf=render

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